WebGrapefruit or grapefruit juice can alter enzymes in the body and affect how drugs are changed in the body before they are eliminated. Grapefruit juice decreases the activity of the cytochrome P450 3A4 (CYP3A4) enzymes that are responsible for breaking down many drugs and toxins. WebFeb 22, 2024 · The grapefruit has been a popular fruit in America for countless years. In some households, in fact, half a grapefruit or even a glass of grapefruit juice is a very normal part of a standard breakfast. Larger than an orange and with inner flesh that can range from pale yellow to deep pink, the grapefruit has a tangy, sweet flavor that sets it …
Grapefruit Juice and Statins - PubMed
WebGrapefruit can block an enzyme that helps your body break down certain medicines. If this enzyme is blocked, too much medication could remain and build up in your bloodstream, … WebGrapefruit Juice and Statins We determined the validity of current medical advice to avoid grapefruit juice consumption while taking 3 widely used statins. A daily glass of grapefruit juice increases blood levels of simvastatin and lovastatin by about 260% if taken at the same time (about 90% if taken 12 hours apart), and atorv … build swain lol
Statin side effects: Weigh the benefits and risks - Mayo Clinic
WebAug 11, 2024 · Grapefruit and statins side effects. Eating grapefruit or drinking grapefruit juice while taking certain statins can increase the statin drug level in your blood, which can increase the chance of side effects. The list of potential adverse effects from statins includes: Digestive problems; Nausea and vomiting; Diarrhea; WebFeb 22, 2024 · Problems arise because chemicals in the fruit can interfere with the enzymes that break down (metabolize) the medication in your digestive system. As a result, the … WebJan 15, 2024 · Consuming large quantities of grapefruit products while taking these statins can lead to greater concentrations of the medication in your bloodstream, increasing your … build swain sp