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Slc gene family

WebThe overview of human SLC superfamily. The human SLC superfamily comprises 386 member proteins that transport a broad spectrum of substrates, such as nutrients, toxins, and prescription drugs. The superfamily members are classified into 52 families, based on the number of predicted or observed transmembrane a-helices (usually 10–14) and ... WebDec 15, 2024 · To construct an SLC family gene signature, we first divided the TCGA LUAD cohort (entire cohort) into a training cohort and a testing cohort at a ratio of …

“SLC-omics” of the kidney: solute transporters along the nephron

WebApr 1, 2009 · Many of these transporters belong to the solute-carrier (SLC) gene superfamily, and include passive transporters, sym-porters and antiporters, as well as mitochondrial and vesicular transporters. The SLC superfamily comprises 55 gene families, having at least 362 putatively functional protein-coding genes . WebApr 30, 2024 · The SLC16A family of monocarboxylate transporters (MCTs) is a subfamily of solute carriers that transport monocarboxylate molecules, including L-lactate and pyruvate, across cell membranes 3.... small wedding venues ann arbor mi https://taylormalloycpa.com

Analysis and update of the human solute carrier (SLC) …

WebApr 19, 2024 · Identification of a Solute Carrier Family-Based Signature for Predicting Overall Survival in Osteosarcoma Identification of a Solute Carrier Family-Based Signature for Predicting Overall Survival in Osteosarcoma Front Genet. 2024 Apr 19;13:849789. doi: 10.3389/fgene.2024.849789. eCollection 2024. Authors Di Zheng 1 , Zhun Wei 1 , Weichun … WebSep 14, 2024 · The solute carrier (SLC) family of proteins is responsible for much of the transport of ions and organic molecules along the renal tubule. In addition, some SLC family proteins mediate housekeeping functions by transporting substrates for metabolism. ... The SLC gene list database was used to generate databases of SLC expression mapped along … WebThe solute-carrier gene (SLC) superfamily encodes membrane-bound transporters. The SLC superfamily comprises 55 gene families having at least 362 putatively functional protein … small wedding venues baltimore

Frontiers Identification of a Six-Gene SLC Family Signature With ...

Category:SLC Family Transporters SpringerLink

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Slc gene family

Frontiers Pan-Cancer Analysis of the Solute Carrier Family 39 …

WebFeb 1, 2009 · The solute carrier (Slc) superfamily is a major group of membrane transport proteins present in mammalian cells. Although Slc transporters play essential and diverse roles in the central... WebJun 21, 2024 · Abnormalities in SLC function in the kidney or placenta may be related to the volume abnormalities observed with this disease. For these reasons, this study aimed to investigate whether 263 haplotype tagging single-nucleotide polymorphisms (SNPs) in 26 members of the SLC gene family are associated with preeclampsia in white and black …

Slc gene family

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WebOct 21, 2024 · The largest groups are SLC family 6 (15 genes), SLC family 2 (14 genes), and SLC family 16 (13 genes) ( Table S5 ). Larger SLC families appear to have several independent origins. SLC family 25, for instance, is composed of 3 large groups of orthologous genes, plus few groups of more recent origin. WebThe overview of human SLC superfamily. The human SLC superfamily comprises 386 member proteins that transport a broad spectrum of substrates, such as nutrients, toxins, …

http://slc.bioparadigms.org/ WebThe SLC8 gene family of sodium-calcium exchangers (NCX) - Structure, function, and regulation in health and disease. Mol Aspects Med. 2013 Apr;34(2-3):220-35. SLC name

WebMay 2, 2024 · The SLC Family Are Candidate Diagnostic and Prognostic Biomarkers in Clear Cell Renal Cell Carcinoma Weiting Kang, 1Meng Zhang, 2 Qiang Wang, 3Da Gu, 4Zhilong Huang, 1,5Hanbo Wang, 1Yuzhu Xiang, 1 Qinghua Xia, 1 Zilian Cui, 1and Xunbo Jin1 Academic Editor: Yu-Chang Tyan Received 12 Dec 2024 Revised 29 Feb 2024 Accepted … WebSolute carrier family. The solute carrier ( SLC) group of membrane transport proteins include over 400 members organized into 66 families. [1] [2] Most members of the SLC group are located in the cell membrane. The SLC gene nomenclature system was originally proposed by the HUGO Gene Nomenclature Committee ( HGNC) and is the basis for the ...

WebApr 10, 2024 · Jeffrey D. Allred, Deseret News. Many had seen Sapporo and Salt Lake City as the strongest 2030 bids, suggesting that Sapporo would be chosen to host in 2030 and Salt Lake City in 2034. However, that was before an Olympic scandal surfaced involving the 2024 Summer Games in Tokyo. The impact on public opinion of that scandal, tied to …

WebJul 26, 2024 · The fumarase deficiency gene has been traced to Joseph Jessop and his first wife, Martha Yeates (14 children). One of their daughters went on to marry co-founder John Barlow – and the rest is... hiking trails in the lehigh valleysmall wedding venues baton rougeWebApr 30, 2024 · The SLC16A family of monocarboxylate transporters (MCTs) is a subfamily of solute carriers that transport monocarboxylate molecules, including L-lactate and … small wedding venues breckenridgeThe solute carrier (SLC) group of membrane transport proteins include over 400 members organized into 66 families. Most members of the SLC group are located in the cell membrane. The SLC gene nomenclature system was originally proposed by the HUGO Gene Nomenclature Committee (HGNC) and is the … See more By convention of the nomenclature system, members within an individual SLC family have greater than 20-25% sequence identity to each other. In contrast, the homology between SLC families is very low to non-existent. … See more The following families are named under SLC: 1. high-affinity glutamate and neutral amino acid transporter See more Putative SLCs, also called atypical SLCs, are novel, plausible secondary active or facilitative transporter proteins that share ancestral background with the known SLCs. The atypical … See more Most members of the SLC group are located in the cell membrane, but some members are located in mitochondria (the most notable one being SLC family 25) or other intracellular organelles. See more Names of individual SLC members have the following format: where: • SLC is the root name (SoLute Carrier) • n = an integer representing a family (e.g., 1-52) • X = a single letter (A, B, C, ...) denoting a subfamily See more • Outline of families • Datasets and Reagents on the Solute Carrier Family • List of proteins at HGNC website See more hiking trails in tokyoWebJan 1, 2009 · The solute-carrier gene (SLC) superfamily encodes membrane-bound transporters. The SLC superfamily comprises 55 gene families having at least 362 … small wedding venues bronx nyWebApr 19, 2024 · Given the important role of SLC family in essential physiological processes including nutrient uptake, ion transport, and waste removal, and that their dysregulation … hiking trails in tioga county nyWebNov 18, 2003 · The SLC series includes genes encoding passive transporters, ion compled transporters and exchangers (see Fig. 1 ). A transporter has been assigned to a specific SLC family if it has at least 20–25% amino acid sequence identity to … small wedding venues boise idaho