WebSep 5, 2024 · Base-pair-driven toehold-mediated strand displacement (BP-TMSD) is a fundamental concept employed for constructing DNA machines and networks with a gamut of applications─from theranostics to computational devices. WebJan 24, 2024 · Toehold-mediated strand displacement (TMSD), a dynamic DNA reaction at nanoscale, is sensitive to single nucleotide mismatch and the output is a single strand which can participate in a variety of downstream reactions to devote to signal amplification. [ 13]
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